San Francisco 49ers VS Buffalo Bills - Live Stream ???? - Video

???? Sunday Night Football Preview: Buffalo Bills vs. San Francisco 49ers
The Buffalo Bills (9-2), one of the hottest teams in the NFL, will host the struggling San Francisco 49ers (5-6) in a primetime Sunday Night Football matchup at Highmark Stadium. Buffalo is coming off a bye week and a statement win against the Kansas City Chiefs, while the 49ers are trying to bounce back after a disheartening blowout loss to the Green Bay Packers.

???? Game Details
Date: Sunday, December 1, 2024
Time: 8:20 PM ET
Location: Highmark Stadium, Orchard Park, NY
TV: NBC
???? Team Comparison
Buffalo Bills
Record: 9-2 (1st in AFC East)
Streak: Won 6 straight games
Key Stats:
Points Per Game: 29.1 (4th in NFL)
Points Allowed Per Game: 19.5 (7th in NFL)
Home Record: 5-0
San Francisco 49ers
Record: 5-6 (4th in NFC West)
Streak: Lost 2 straight games
Key Stats:
Points Per Game: 23.6 (14th in NFL)
Points Allowed Per Game: 23.6 (20th in NFL)
Road Record: 2-3
???? Matchups to Watch
1. Josh Allen vs. 49ers' Defense
Allen is having another stellar season, combining for 2,859 total yards and 23 touchdowns. San Francisco's defense, led by Fred Warner and Nick Bosa, ranks 6th against the pass but has struggled to limit explosive plays recently.

2. Christian McCaffrey vs. Bills’ Front Seven
Despite injuries, McCaffrey remains a dual-threat. He’ll test a Bills defense that ranks 14th against the run but excels at limiting scoring opportunities.

3. George Kittle vs. Bills’ Secondary
Kittle has been the 49ers' most consistent offensive weapon. The Bills' linebackers, led by Dorian Williams, will need to contain Kittle to limit San Francisco’s big-play potential.

???? Injury Updates
Buffalo Bills
RB James Cook: Active (limited practice this week).
WR Khalil Shakir: Expected to play despite a minor ankle injury.
DT Ed Oliver: Questionable (knee).
San Francisco 49ers
QB Brock Purdy: Questionable (shoulder).
DE Nick Bosa: Questionable (hip).
OT Trent Williams: Questionable (ankle).
WR Deebo Samuel: Out (hamstring).
???? Betting Insights
Latest Odds
Spread: Bills -6.5
Moneyline: Bills -282, 49ers +229
Over/Under: 44.5
Betting Trends
Bills are 7-4 ATS this season.
49ers are 3-7 ATS in their last 10 games.
The over has hit in 63.6% of Bills games this season.
The Bills are 9-0 after a bye since 2015.
????️ Keys to Victory
Buffalo Bills
Start Fast: Take advantage of San Francisco’s slow starts and force them to play catch-up.
Pressure Purdy: If Brock Purdy plays, disrupt his rhythm and capitalize on San Francisco’s banged-up offensive line.
Efficient Red Zone Play: Turn drives into touchdowns, not field goals.
San Francisco 49ers
Control the Clock: Lean on McCaffrey and the run game to limit Buffalo’s offensive opportunities.
Win the Turnover Battle: Force Josh Allen into mistakes and capitalize on short fields.
Exploit Mismatches: Use Kittle to create mismatches in the middle of the field.
???? Prediction
The Bills are playing at an elite level and are well-rested after their bye week. Meanwhile, the 49ers are riddled with injuries and face a tough cross-country road game in cold weather. Buffalo’s high-powered offense, led by Josh Allen, should prove too much for a depleted San Francisco squad.

Final Score Prediction: Bills 31, 49ers 17

Buffalo extends its win streak to seven and inches closer to securing the top seed in the AFC. Meanwhile, the 49ers face an uphill battle to keep their playoff hopes alive.