Do This To Quiet the Voice That Says Keep Eating. With or Without Ozempic & Mounjaro.
About this video
Why you eat when you're not hungry, and how to stop cravings with or without medications namely Ozempic, mounjaro, zepbound, foundayo or wegovy. A pathologist reads the published studies on night eating, food noise, hunger hormones, and why the weight comes back after a diet. Normal is the average of a sick population. The bar is too low, and we can do better than the bar. It's 9:30 pm. You had dinner. You're standing at the open fridge anyway. I went through the peer-reviewed research on that moment, and I think the usual explanation, willpower, starts in the wrong place. Short sleep turns the signal up: 4 hours of sleep raised hunger 24%, and 1.2 more hours cut intake by about 270 calories a day with no diet. Your circadian clock peaks hunger around 8 pm on its own. Ultra-processed food within reach added about 500 calories a day in an NIH inpatient trial. And losing weight itself turns the signal up: hunger hormones were still displaced a full year after a diet ended. Then the drug: what semaglutide (Ozempic, Wegovy) did to intake in a placebo-controlled trial, what "food noise" means, whether cravings alone are a reason to take Ozempic or Mounjaro, and what happened when people stopped. WHAT I'D DO THIS WEEK (clear it with your physician first) Tonight, at the fridge, ask what turned the signal up today. If you sleep under 6.5 hours, fix that before you judge your eating. Protein at breakfast; the trial used 35 g. 3 smaller meals with protein, fed all day instead of good all day. Move the 9 pm food 2 minutes out of reach, put protein where it was, and plan a snack for the hour you lose to. Regained more than once? Ask your physician whether the biology of regain is something to treat. WATCH NEXT Long Term Side Effects of Mounjao and Ozempic: https://youtu.be/oPghVzTAyFg Why Ozempic and Mounjaro plateau, and What To Do: https://youtu.be/aWhxfJMUOkA Sleep and weight loss, the full video: https://youtu.be/eIxKdaCRUt4 How To Use Weightloss Medications As a Bridge While You Build Foundations: https://youtu.be/2LIsLwBSr_c THE GLP-1 METHOD A 90-day program built on the foundations that remain when the medication is reduced or stopped. Next cohort begins January 2, 2027. Free waitlist: https://getuninflamed.com ABOUT: Dr. Amin Hedayat is a triple board certified physician and pathologist, and an Assistant Clinical Professor. In the last few years he has focused on metabolic health and obesity medicine. New video every Saturday at 7 am PT. DISCLAIMERS: I'm not paid by or affiliated with any pharmaceutical company, compounding pharmacy, or peptide seller. This is educational content, not medical advice. Decisions about starting, changing, or stopping any medication belong with you and your prescribing physician. CHAPTERS 00:00:00 Not hungry, still eating: where willpower goes wrong 00:02:10 How to judge health claims: published, hypothesis, unknown 00:03:37 Sleep: 4 hours raised hunger 24%, 1.2 more hours cut 270 calories 00:05:30 How to support this channel (free) 00:06:40 Your hunger clock: why cravings peak at 8 pm 00:08:30 Should you "never eat after 7"? 00:09:25 Your kitchen: the NIH ultra-processed food trial 00:11:35 Breakfast: 35 g of protein and evening snacking 00:13:11 "Good all day": why restricting sets up night eating 00:14:39 What you're sold: willpower, gummies, cortisol 00:17:00 Ozempic and food noise: what the semaglutide trial measured 00:19:30 What "food noise" actually means 00:21:22 Are cravings a reason to take Ozempic or Mounjaro? 00:23:16 A year after the diet: hunger hormones still up (NEJM) 00:24:50 What happens when you stop Ozempic or Mounjaro 00:26:25 The GLP-1 Method (January 2, 2027) 00:27:05 What to do this week: 9 pm, one bite, or alone REFERENCES: 1. Spiegel 2004, Ann Intern Med. https://doi.org/10.7326/0003-4819-141-11-200412070-00008 2. Tasali 2022, JAMA Intern Med. https://doi.org/10.1001/jamainternmed.2021.8098 3. Scheer 2013, Obesity. https://doi.org/10.1002/oby.20351 4. Hall 2019, Cell Metab. https://doi.org/10.1016/j.cmet.2019.05.008 5. Leidy 2013, Am J Clin Nutr. https://doi.org/10.3945/ajcn.112.053116 6. Blundell 2017, Diabetes Obes Metab (Novo Nordisk funded). https://doi.org/10.1111/dom.12932 7. Rutigliani 2026, Obes Rev. https://doi.org/10.1111/obr.70148 8. Dhurandhar 2025, Nutr Diabetes. https://doi.org/10.1038/s41387-025-00382-x 9. Dhurandhar 2025, Appetite. https://doi.org/10.1016/j.appet.2025.108339 10. Brewis 2026, Appetite. https://doi.org/10.1016/j.appet.2026.108700 11. Sumithran 2011, N Engl J Med. https://doi.org/10.1056/NEJMoa1105816 12. Aronne 2024, JAMA (SURMOUNT-4). https://doi.org/10.1001/jama.2023.24945 13. Wilding 2022, Diabetes Obes Metab (STEP 1 extension). https://doi.org/10.1111/dom.14725 14. Eli Lilly, April 1, 2026, Foundayo (orforglipron) FDA approval, investor.lilly.com #FoodNoise #Cravings #Ozempic #NightEating #Mounjaro #WeightLoss
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